Multidisciplinary Consensus Conference on Precursor Lesions of the Genitourinary Organs
On September 12, 2024, the International Society of Urological Pathology will host a “Multidisciplinary Consensus Conference on Cancer Precursor Lesions of the Genitourinary Organs“, open to members and non-member clinicians and scientists in pathology, urology, oncology, and related fields, immediately after the 36th European Congress of Pathology (ECP), in the beautiful city of Florence, Italy. This consensus will be in person, without a hybrid format.
This conference will be hosted at the Hotel Albani Firenze (address: Via Fiume, 12, 50123 Firenze FI, Italy). The hotel is approximately 450 meters away from the Congress Center, Fortezza da Basso.
The meeting objectives are:
– Define established and putative precursor lesions of genitourinary organs
– Refine classification scheme/terminology and diagnostic criteria
– Provide recommendations for pathology reporting
– Provide recommendations for ancillary studies and diagnostic work-up, including immunostaining and molecular testing in different clinical settings
– Provide literature review to aid developing guidelines for clinical management
This Consensus will be Co-Chaired by ISUP members, Dr. Liang Cheng (Providence, RI, USA), and Dr. Glen Kristiansen (Bonn, Germany).
Agenda
8:00 – 8:20 am Coffee and Registration
8:20 – 8:30 am Welcome & Opening Remarks
Liang Cheng & Glen Kristiansen (Conference Chairpersons)
8:30- 10:30 am Working Group 1 | Precursor Lesions of the Prostate
Introduction Kenneth A. Iczkowski & Geert JLH van Leenders (WG1 Chairpersons)
Subgroup 1 High grade prostatic intraepithelial neoplasia (HGPIN)
– Molecular origns of prostate cancer (Angelo DeMarzo)
– Historical perspectives and survey findings (Kenneth Iczkowski)
– Contemporary perspective (Murali Varma)
– Summary/Proposals/Voting/Final Statements (David Berman)
Subgroup 2 Intraductal carcinoma (IDC)
– Current perspective, molecular data, and differential diagnosis (Massimo Loda)
– Summary/Proposals/Voting/Final Statements (Massimo Loda)
Subgroup 3 Atypical intraductal proliferation (AIP)
– Diagnostic criteria (Nancy Greenland)
– Molecular correlates (Tamara Lotan)
– Clinicopathologic correlates (Alessia Cimadamore)
– Summary/Proposals/Voting/Final Statemens (Samson Fine)
Subgroup 4 Proliferative inflammatory atrophy and atypical adenomatous hyperplasia
– Current perspective & molecular evidence (Angelo DeMarzo)
– Summary/Proposals//Voting/Final Statements (Angelo DeMarzo)
10:30 – 10:45 am Coffee break
10:45 – 12:15 pm Working Group 2 | Precursor Lesions of the Urinary Bladder
Introduction Michelle Downes & Maria Raspollini (WG2 Chairpersons)
Flat lesions Gladell Paner
Glandular lesions Antonio Lopez-Beltran
Papillary lesions Steven Shen
Squamous lesions Donna Hansel
Clinical focus Roberto Contieri
12:15 – 1:15 pm Group photo and lunch break
1:15 – 2:30 pm Working Group 3 | Precursor Lesions of the Kidney
Introduction Sean Williamson & Holger Moch (WG3 Chairpersons)
Overview on selected topics and general concepts
- Progression pathways of ccRCC Holger Moch
- CCP tumor and PRCC progression Sean Williamson
- chRCC progression and cell of origin concept Rohit Mehra
Objective report of polled questions/Discussion/Voting Sean Williamson
Final statements and closing remarks Holger Moch
2:30 – 2:45 pm Coffee break
2:45 – 3:45 pm Working Group 4 | Precursor Lesions of the Testis
Introduction Felix Bremmer & Satish Tickoo (WG4 Chairpersons)
Overview of testicular precursor lesions Felix Bremmer
Questionnaire data presentation Maurizio Colecchia
Summary/Proposals/Voting/Final Statements Satish Tickoo
3:45 – 4:55 pm Working Group 5 | Precursor Lesions of the Penis
Introduction Santosh Menon & Antonio Cubilla (WG5 Chairpersons)
Overview of penile precursor lesions Antonio Cubilla
Objective report of polled questions Elsa Velazquez
Summary/Proposals/Discussion Pheroze Tamboli
Voting/Final statements Santosh Menon
4:55 – 5:00 pm Closing Remarks by Glen Kristiansen & Liang Cheng
General questions: Katrina Collins katcoll@iu.edu and/or Nancy Greenland nancy.greenland@ucsf.edu
Local organizers: Maria R. Raspollini, Alessia Cimadamore, Matteo Brunelli
Future meetings:
IAP (International Academy of Pathology): Biennial meetings (ie. every second year) in August, September or October.
AUA (American Urological Association): Annual meetings in May or June.
EAU (European Association of Urology): Annual meetings in March or April.
SIU (Société Internationale d’Urologie): Annual meetings in September or October.
APIAP (Asian Pacific IAP): Biennial meetings.
Latin American Meeting of Uropathology: Annual meetings.