Case ID: 1270

Publication date: 16 Apr, 2024

Consensus grade: Collecting duct carcinoma

User Diagnosis Difficulty Comment
Pathologist 1 Collecting duct carcinoma Typical
Pathologist 2 Collecting duct carcinoma Typical
Pathologist 3 Collecting duct carcinoma Typical
Pathologist 4 Collecting duct carcinoma Typical
Pathologist 5 Collecting duct carcinoma Typical
Pathologist 6 Collecting duct carcinoma Typical
Pathologist 7 Collecting duct carcinoma Not typical

The images shown suggest collecting duct carcinoma (CDC)-like features. However, this morphology is not specific for CDC. With only selected images, it is difficult to be certain.

Pathologist 8 Insufficient tumor for diagnosis Not typical
Pathologist 9 Other Not typical
Pathologist 10 Collecting duct carcinoma Typical
Pathologist 11 Collecting duct carcinoma Typical
Pathologist 12 Collecting duct carcinoma Typical
Pathologist 13 Collecting duct carcinoma Typical
Pathologist 14 Collecting duct carcinoma Typical
Pathologist 15 Collecting duct carcinoma Not typical

Could it easily be TCC, I would extensively sample tumor with concern to renal pelvis area

Pathologist 16 Collecting duct carcinoma Typical
Pathologist 17 Collecting duct carcinoma Not typical
Pathologist 18 Collecting duct carcinoma Typical


Case description (by case creator):

This is a high grade tumor composed of infiltrating tubules and ducts. there is a marked desmoplastic response in the stroma. The cells have a high nuclear grade with particularly prominent nucleoli.