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Case ID: 640

Publication date: 31 Jan, 2025

Consensus grade: High-grade papillary urothelial carcinoma (HG-PUC)

User Diagnosis Difficulty Comment
Pathologist 1 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 2 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 3 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 4 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 5 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 6 High-grade papillary urothelial carcinoma (HG-PUC) Typical

supplementary cuts would be useful to e sure that there is no invasion, would also say Cis associated

Pathologist 7 High-grade papillary urothelial carcinoma (HG-PUC) Borderline higher
Pathologist 8 High-grade papillary urothelial carcinoma (HG-PUC) Borderline higher
Pathologist 9 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 10 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 11 High-grade papillary urothelial carcinoma (HG-PUC) Typical

No specific comment.

Pathologist 12 High-grade papillary urothelial carcinoma (HG-PUC) Bordering on lower
Pathologist 13 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 14 Low-grade papillary urothelial carcinoma (LG-PUC) Bordering on higher

Squamous metaplasia

Pathologist 15 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 16 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 17 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 18 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 19 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 20 High-grade papillary urothelial carcinoma (HG-PUC) Typical

Squamous differentiation

Pathologist 21 High-grade papillary urothelial carcinoma (HG-PUC) Typical
Pathologist 22 High-grade papillary urothelial carcinoma (HG-PUC) Typical


Case description (by case creator):

High grade papillary urothelial carcinoma, invasive in the lamina propria. Presence of squamous differentiation. Presence of carcinoma in situ adjacent to the papillary lesion, within von Brunn nests.