5345 | Bladder Flat Lesions

Case ID: 403

Publication date: 10 Feb, 2025

Consensus grade: Carcinoma in situ (CIS)

Show diagnosis by expert panel members

User	Diagnosis	Difficulty	Comment
Pathologist 1	Carcinoma in situ (CIS)	Typical
Pathologist 2	Carcinoma in situ (CIS)	Typical	Pagetoid spread into von Brunn's nest
Pathologist 3	Carcinoma in situ (CIS)	Typical
Pathologist 4	Carcinoma in situ (CIS)	Typical	No specific comment.
Pathologist 5	Carcinoma in situ (CIS)	Borderline lower
Pathologist 6	Carcinoma in situ (CIS)	Typical
Pathologist 7	Carcinoma in situ (CIS)	Typical
Pathologist 8	Carcinoma in situ (CIS)	Typical
Pathologist 9	Carcinoma in situ (CIS)	Typical
Pathologist 10	Carcinoma in situ (CIS)	Typical
Pathologist 11	Carcinoma in situ (CIS)	Typical
Pathologist 12	Carcinoma in situ (CIS)	Typical	partially pagetoid
Pathologist 13	Carcinoma in situ (CIS)	Typical
Pathologist 14	Carcinoma in situ (CIS)	Typical
Pathologist 15	Carcinoma in situ (CIS)	Typical
Pathologist 16	Carcinoma in situ (CIS)	Typical	pagetoid
Pathologist 17	Carcinoma in situ (CIS)	Typical
Pathologist 18	Carcinoma in situ (CIS)	Typical
Pathologist 19	Carcinoma in situ (CIS)	Typical

Case description (by case creator):

Pagetoid involvement of von Brunn nests by malignant cells. The surface urothelium displays loss of cohesion

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