Case ID: 80
Publication date: 03 May, 2024
Consensus grade: Atypia/dysplasia
Show diagnosis by expert panel members| User | Diagnosis | Difficulty | Comment |
|---|---|---|---|
| Pathologist 1 | Atypia/dysplasia | Typical | |
| Pathologist 2 | Atypia/dysplasia | Borderline higher | |
| Pathologist 3 | Atypia/dysplasia | Typical | |
| Pathologist 4 | Atypia/dysplasia | Typical | |
| Pathologist 5 | Atypia/dysplasia | Typical | |
| Pathologist 6 | Atypia/dysplasia | Typical |
Needs IHCH, Images og IHCH without antibody do not help... |
| Pathologist 7 | Atypia/dysplasia | Typical | |
| Pathologist 8 | Atypia/dysplasia | Typical |
what kind of immuno is this?? |
| Pathologist 9 | Reactive atypia | Typical | |
| Pathologist 10 | Atypia/dysplasia | Borderline higher | |
| Pathologist 11 | Atypia/dysplasia | Borderline higher | |
| Pathologist 12 | Atypia/dysplasia | Borderline lower | |
| Pathologist 13 | Reactive atypia | Typical |
No specific comment. |
| Pathologist 14 | Atypia/dysplasia | Bordering on higher | |
| Pathologist 15 | Reactive atypia | Bordering on higher | |
| Pathologist 16 | Carcinoma in situ (CIS) | Typical | |
| Pathologist 17 | Atypia/dysplasia | Bordering on higher | |
| Pathologist 18 | Reactive atypia | Bordering on higher | |
| Pathologist 19 | Carcinoma in situ (CIS) | Bordering on lower | |
| Pathologist 20 | Atypia/dysplasia | Bordering on higher |
Though diffuse CK20 positivity, nuclei not high-grade enouth |
| Pathologist 21 | Atypia/dysplasia | Bordering on higher | |
| Pathologist 22 | Atypia/dysplasia | Bordering on higher |
Case description (by case creator):
The first two images illustrate normal urothelium for comparison. There is a granuloma in the lamina propria, consistent with BGC therapy. The other images illustrate flat urothelium that shows variable loss of polarity and nuclear aytpia with enlargement and some hyperchromasia. CK20 immunohistochemistry shows diffuse full thickness positivity in the urothelium.
